| Clinical Usefulness of MRA and Risk Factor Analysis for Occlusive
Cerebrovascular Disease in Geriatric Patients |
|
Sung Sam Jung |
|
Department of Neurosurgery, Eulji University School of Medicine, Daejeon, Korea |
| 노인 연령층에서 뇌혈관 협착증의 진단: MRA의
유용성 및 위험인자 분석 |
|
정 성 삼 |
|
을지대학교 의과대학 신경외과학교실 |
|
|
| Abstract |
Objective
s: The aim of this study is to evaluate the role of magnetic resonance angiography (MRA) in detecting
occlussive cerebrovascular disease in geriatric patients and to examine the relationship between cerebrovascular
lesions detected on MRA and vascular risk factors.
Materials
& Methods: We retrospectively assessed 212 patients who visited our institution and underwent both
brain magnetic resonance imaging (MRI) and three-dimensional, time-of-flight MRA of the head. We evaluated stenotic
or occlusive lesions of the intracranial arteries using MRA. Age, sex, history of hypertension, history of ischemic heart
disease, family history of cerebrovascular disease, HbA1c, total cholesterol, fasting triglyceride, high density lipoprotein,
low density lipoprotein, hematocrit, smoking and left ventricular hypertrophy (LVH) on ECG were included in the
analysis.
Results
Forty-nine patients (23.1%) had stenotic or occlusive lesions of the intracranial arteries. The distribution
of stenotic or occlusive vascular lesions were correlated with the location of infarction in 25 of the 49 positive cases
(51%). MRA provided additional information not obtained from the MRI in 24 cases. Univariate analysis showed
that age, hypertension, LDL hypercholesterolemia and HbA1c were significantly correlated with atherosclerotic lesions of
the intracranial arteries. Multiple logistic regression analysis showed that significant and independent predictors for
atherosclerotic lesions of the intracranial arteries were HbA1c, LDL hypercholesterolemia and hypertension.
Conclusion
The present study suggests that atherosclerotic lesion of the intracranial arteries detected in MRA is
related to LDL hypercholesterolemia, hypertension and HbA1c in geriatric patients. MRA is considered to be a clinically
useful method for screening cerebrovascular disease in geriatric patients with risk factors and selecting high-yield patients
for conventional angiography. |
| Key Words:
Magnetic resonance angiographyㆍRisk factorㆍCerebrovascular diseaseㆍGeriatric |
|
PDF Links
Download Citation
