Journal of Korean Society of Geriatric Neurosurgery 2007;3(1):30-37.
Published online June 30, 2007.
Clinical Usefulness of MRA and Risk Factor Analysis for Occlusive Cerebrovascular Disease in Geriatric Patients
Sung Sam Jung

Department of Neurosurgery, Eulji University School of Medicine, Daejeon, Korea

노인 연령층에서 뇌혈관 협착증의 진단: MRA의 유용성 및 위험인자 분석

정 성 삼

을지대학교 의과대학 신경외과학교실

s: The aim of this study is to evaluate the role of magnetic resonance angiography (MRA) in detecting occlussive cerebrovascular disease in geriatric patients and to examine the relationship between cerebrovascular lesions detected on MRA and vascular risk factors.
& Methods: We retrospectively assessed 212 patients who visited our institution and underwent both brain magnetic resonance imaging (MRI) and three-dimensional, time-of-flight MRA of the head. We evaluated stenotic or occlusive lesions of the intracranial arteries using MRA. Age, sex, history of hypertension, history of ischemic heart disease, family history of cerebrovascular disease, HbA1c, total cholesterol, fasting triglyceride, high density lipoprotein, low density lipoprotein, hematocrit, smoking and left ventricular hypertrophy (LVH) on ECG were included in the analysis.
Forty-nine patients (23.1%) had stenotic or occlusive lesions of the intracranial arteries. The distribution of stenotic or occlusive vascular lesions were correlated with the location of infarction in 25 of the 49 positive cases (51%). MRA provided additional information not obtained from the MRI in 24 cases. Univariate analysis showed that age, hypertension, LDL hypercholesterolemia and HbA1c were significantly correlated with atherosclerotic lesions of the intracranial arteries. Multiple logistic regression analysis showed that significant and independent predictors for atherosclerotic lesions of the intracranial arteries were HbA1c, LDL hypercholesterolemia and hypertension.
The present study suggests that atherosclerotic lesion of the intracranial arteries detected in MRA is related to LDL hypercholesterolemia, hypertension and HbA1c in geriatric patients. MRA is considered to be a clinically useful method for screening cerebrovascular disease in geriatric patients with risk factors and selecting high-yield patients for conventional angiography.
Key Words: Magnetic resonance angiographyㆍRisk factorㆍCerebrovascular diseaseㆍGeriatric

Editorial Office
21, Namdong-daero 774beon-gil, Namdong-gu, Incheon 21565, Korea
Tel: +82-32-460-3304    Fax: +82-32-460-3899    E-mail:                

Copyright © 2024 by Korean Society of Geriatric Neurosurgery.

Developed in M2PI

Close layer
prev next