Journal of Korean Society of Geriatric Neurosurgery 2016;12(2):140-145.
Published online September 30, 2016.
Benefits of Vertebroplasty in Preventing Kyphotic Deformity in Osteoporotic Vertebral Compression Fracture of Thoracolumbar Junction
Hyun-Mook Kwon , Sang-Pyung Lee , Jin-Wook Baek , Seong-Hwan Kim
Departement of Neurosurgery, Cheju Halla General Hospital, Jeju, Korea
Abstract
Objective
The purpose of this study is to evaluate the effect of percutaneous vertebroplasty (PVP) on the progression of body compression and kyphosis in osteoporotic compression fractures of thoracolumbar spine, compared with conservative therapy.
Methods
One hundred five patients who were aged 65 years or older with osteoporotic compression fractures in thoracolumbar (T11-L1) levels were included in this study. The patients were categorized into the conservative therapy group and the vertebroplasty group. The kyphotic angle and fractured vertebral height was measured on 2 weeks, 1 month, 3 months, and the last follow-up. The cement infusion ratios were calculated after vertebroplasty, by means of dividing total volume of infused cement by fractured body volume.
Results
The mean changes of the kyphotic angle between initial and final follow‐up in conservative therapy and vertebroplasty group were 6.2 (SD=6.4, p=0.01) and 1.4 (SD=4.5, p=0.01). The mean change of the compression ratio between initial and final follow-up in conservative therapy and vertebroplasty group was 3.1 (SD=3.3, p=0.01) and 0.9 (SD=2.1, p=0.01) on each. Although, the kyphotic angle and compression ratio were progressed in both groups, the progression rates were higher in conservative therapy group. In bivariate correlation analysis, the differences of the values between two groups showed statistical significance.
Conclusion
This study statistically analyzed the superiority of PVP on preventing vertebral compression and kyphosis in patients with osteoporotic compression fracture, over conservative therapy.
Key Words: Vertebroplasty, Kyphosis, Fractures, Compression


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