| The Relationship Between the Patients’ Age and Other Clinical Variables in Patients with Medically Refractory Cerebral Vasospasm |
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Sang-Young Kim , Ki-Hong Kim , Jae-Hoon Cho , Young-Don Kim |
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Department of Neurosurgery, Daegu Catholic University School of Medicine, Daegu, Korea |
| 무반응성 뇌혈관연축 환자에서 나이와 다른 임상인자들 및 치료 결과들과의 관계 |
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김상영·김기홍·조재훈·김영돈 |
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대구가톨릭대학교 의과대학 신경외과학교실 |
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| Abstract |
Objective
The objective of this study was to investigate the relationship between the patients’ age and other clinical variables in patients with medically refractory cerebral vasospasm(CV) following subarachnoid hemorrhage (SAH).
Methods
During the 36 months between January 2011 and December 2013, 275 patients were treated at our institute for SAH due to a ruptured intracranial aneurysm. Among 275 patients, 26 patients (9.5%) met the inclusion criteria. Of the 26 patients, 14 were younger than 50 years-old and 12 were older than 50 years-old. For each patient treated with intra-arterial nimodipine infusion, a retrospective review of medical records was conducted.
Results
Younger patients had 2.9±1.2 vasospasm segment and older patients had 2.0±0.7 vasospasm segment (p=0.046). Younger patients had 4.6±0.6 GOS scores and older patients had 3.6±1.3 GOS scores at 3 months (p=0.022). There was no significant difference in mean middle cerebral artery velocities on transcranial Doppler ultrasound (p=0.393), angiographic response after angioplasty (p=0.867) and need for repetitive angioplasty (p=0.462) according to patients’ age.
Conclusion
Older age was not associated with a wide extent of vasospasm in patients with medically refractory cerebral vasospasm(CV). However, older patients had poorer GOS scores at 3 months than younger patients. |
| Key Words:
AgeㆍCerebral vasospasmㆍIntra-arterialㆍNimodipineㆍInfusion |
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