Application of the Korean FRAX (Fracture Risk Assessment
Tool) Model in Elderly with Osteoporotic Vertebral
Compression Fracture |
Jae Sik Shin , Pyung Goo Cho , Sung Han Oh , Bong Sub Chung |
Department of Neurosurgery, Bundang Jesaeng General Hospital, Gyeonggi, Korea |
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Abstract |
Objective The Fracture Risk Assessment Tool (FRAX) was developed by the World Health Organization (WHO) to
provide a prediction tool for assessing individual’s risk of fracture. In this study, we wanted to know the FRAX availability
in Korean elderly patients who had proven osteoporotic vertebral compression fracture.
Methods Retrospectively, we evaluated 82 patients aged over 65 years who had acute osteoporotic vertebral compression
fracture from Jan 2009 to Jan 2014. The patients were divided into two groups: No recurrent fracture in Group
A (63) and recurrent fracture in Group B (19). We analyzed their epidemiology and the location of recurrent fracture.
In particular, we evaluated the correlation between the recurrent osteoporotic fractures and each risk factor of FRAX.
Results Total 19 of 82 patients have developed the recurrent osteoporotic fractures. Of the all FRAX risk factors,
previous fracture and rheumatoid arthritis were significant factors (p=0.014, p=0.009, respectively). T-score of Femur
was -2.95±0.98 in Group A and -3.20±0.85 in Group B. In Group A, major part of FRAX score was 6.44±5.54 and femur
part of FRAX score was 12.63±7.75. In Group B, major part of FRAX score was 8.82±8.71 and femur part of FRAX
score was 16.20±10.87. However, there were no statistical significances between groups.
Conclusion The current study found that female, previous fracture and rheumatoid arthritis were meaningful risk
factors of the recurrent osteoporotic fracture. However, major and femur part of FRAX scores were not significant between
groups. We should determine the cut-off values on FRAX as treatment threshold for major osteoporotic fractures
in elderly through cohort study. |
Key Words:
Bone mineral densityㆍCompression fractureㆍFRAXㆍOsteoporosisㆍRecurrentㆍRisk factors |
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