| Analysis of the Outcomes of CyberKnife surgery for Meningioma in a Single Center Analysis |
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Gyeong O Go1 , Kyung Bum Park1 , Dong Ho Kang1 , In Sung Park1,2 , Jin-Myung Jung1 , Jong Woo Han1 |
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1Department of Neurosurgery, Gyeongsang National University School of Medicine, Jinju, Korea
2Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju, Korea |
| 노인 환자에서 수막종에 대한 사이버나이프 치료 결과의 분석 |
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고경오1ㆍ박경범1ㆍ강동호1ㆍ박인성1,2ㆍ정진명1ㆍ한종우1 |
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경상대학교 의과대학 신경외과학교실1, 경상대학교 건강과학연구원2 |
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| Abstract |
Objective
In this study, we reviewed the results of CyberKnife radiosurgical treatment of meningiomas in a single treatment center.
Methods
This was a retrospective analysis of patients aged 65 or more that underwent CyberKnife radiosurgical treatment between February
2010 and August 2012. All patients participated in follow up reviews over an average of 17.5±10.1 months. 24 tumors were treated over
the study interval. The mean radiation dose was 2993.3±265.7 cGy (range 2410-3846 cGy), and a mean of 81.1±3.4% (range 72-89%) isodose
line. Using the caliper method, tumors were divided into groups of ≥3 cm or <3 cm. Outcomes were estimated clinically using medical records
and using magnetic resonance imaging (MRI) or computed tomography (CT) in the follow up.
Results
24 tumors were treated, and the follow up MRI revealed a decreased tumor size in 24 lesions, a decreased size in 16 lesions, an
unchanged size in seven lesions, and an increased size in one lesion. Two patients died, and one patient had been histopathologically diagnosed
as atypical meningioma at prior operation. Overall, tumor control was 95.9%. There were no significant differences between the outcomes
in the two tumor size (≥3 cm and <3 cm) groups (p=0.292), and no significant radiation-related cranial nerve injuries were observed.
Conclusion
CyberKnife is an effective treatment for small (2.5 cm average diameter) benign meningioma and is recommended for elderly as
alternative treatment. And further studies that evaluate the long-term outcomes of CyberKnife are needed. |
| Key Words:
MeningiomaㆍStereotacticㆍCyberKnifeㆍRadiosurgeryㆍOutcomes |
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