| Gamma Knife Radiosurgery in the Geriatric Age Patients with Pituitary Adenomas |
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Soo Hwan Lee1 , Seong Tae Kim1 , Won Hee Lee1 , Kun Soo Lee1 , Seong Hwa Paeng1 , Se Yeong Pyo1 , Yeong Gyun Jeong1 , Moo Seong Kim1 , Yong Tae Jung1 , Hae Woong Jeong2 , Yang Won Kim3 , Sang Jin Kim4 |
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Department of Neurosurgery, Inje University School of Medicine, Busan Paik Hospital, Busan, Korea |
| 노인에서 발생한 뇌하수체선종의 감마나이프 수술 |
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이수환1ㆍ김성태1ㆍ이원희1ㆍ이근수1ㆍ팽성화1ㆍ표세영1ㆍ정영균1ㆍ김무성1ㆍ정용태1ㆍ정해웅2ㆍ김양원3ㆍ김상진4 |
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인제대학교 의과대학 부산백병원 신경외과학교실1, 영상의학과교실2, 응급의학과교실3, 신경과교실4 |
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| Abstract |
Objective
Pituitary adenomas produce adverse symptoms by compression of adjacent cranial nerves, brain, and/or hypersecretion of hormones. We assess the effect of the Gamma Knife radiosurgery for pituitary adenomas in geriatric ages.
Methods
Thirteen geriatric pituitary adenoma patients were treated with Gamma knife radiosurgery from November 1994 to December 2011. There were 2 cases of prolactinoma, 3 cases of growth hormone secreting adenoma, 8 cases of non-functioning adenoma. 2 cases underwent transsphenoidal resective operation. The mean tumor volume was 5.4 cc and the mean marginal dose was 14.3 Gy and the mean matimal dose was 26.2 Gy, the mean follow-up period was 28.6 months with range from 12 months to 67 months.
Results
On follow-up magnetic resonance imaging study after Gamma knife surgery, 10 cases showed reduction in size, 3 cases showed no change in size. In the hormonal result, 2 cases of 2 prolactiomas patients had decreased prolactin hypersecretion, and 2 case out of 3 acromegalic patient had decreased growth hormone hypersecretion and 1 case shows clinical cure. There was no complications.
Conclusion
Gamma knife radiosurgery can be effective and safe method for the treatment of geriatric pituitary adenoma. |
| Key Words:
Pituitary adenomaㆍGamma knife radiosurgery |
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