Analysis of Prognostic Factors Associated with Corticospinal Tract
Injury by Using Diffusion Tensor Imaging in Old Patients with
Hypertensive Intracerebral Hemorrhage |
Moon Young Chung , In Bo Han , Ryoong Huh , Sang Sup Chung |
Department of Neurosurgery, CHA University, Bundang CHA Hospital, Sungnam, Korea |
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Abstract |
Objective Hypertensive intracerebral hemorrhage (ICH) may be accompanied by motor impairment of various degrees. Corticospinal
tract of patient affected with hypertensive ICH was examined by diffusion tensor image (DTI). The purpose of this study is to analyze
the relation between the extents of the damage of corticospinal tract passed through posterior limb of the internal capsule and motor
function prognosis in patients with hypertensive ICH.
Methods Thirty six patients examined for this study. The extents of the invasion of posterior limb of the internal capsule were
converted into fraction anisotropy (FA) ratio, and results of initial manual motor test was compared with results of that about several
weeks later. This study was designed to investigate correlations between FA ratio and improvement aspect of motor function by
analyzing other factors, such as hypertension, diabetes, and amounts of hemorrhage. The correlation between FA ratio and improvement
of motor function was analyzed by Pearson’s correlation analysis.
Results Motor function improvement was significantly correlated with FA ratio. Volume of hemorrhage related with motor function
at admission, but it is useless for estimating prognosis. Hypertension and diabetes are not correlated with motor function improvement
in this study.
Conclusion In patients with hypertensive ICH, FA ratio that is calculated from FA values of MR DTI could be a prognostic factor
of motor function improvement. |
Key Words:
Intracranial Hemorrhage, HypertensiveㆍDiffusion MRIㆍCorticospinal TractㆍFunction Recovery |
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