Journal of Korean Society of Geriatric Neurosurgery 2009;5(1):51-55.
Published online June 30, 2009.
Analysis of Prognostic Factors Associated with Corticospinal Tract Injury by Using Diffusion Tensor Imaging in Old Patients with Hypertensive Intracerebral Hemorrhage
Moon Young Chung , In Bo Han , Ryoong Huh , Sang Sup Chung
Department of Neurosurgery, CHA University, Bundang CHA Hospital, Sungnam, Korea
Abstract
Objective
Hypertensive intracerebral hemorrhage (ICH) may be accompanied by motor impairment of various degrees. Corticospinal tract of patient affected with hypertensive ICH was examined by diffusion tensor image (DTI). The purpose of this study is to analyze the relation between the extents of the damage of corticospinal tract passed through posterior limb of the internal capsule and motor function prognosis in patients with hypertensive ICH.
Methods
Thirty six patients examined for this study. The extents of the invasion of posterior limb of the internal capsule were converted into fraction anisotropy (FA) ratio, and results of initial manual motor test was compared with results of that about several weeks later. This study was designed to investigate correlations between FA ratio and improvement aspect of motor function by analyzing other factors, such as hypertension, diabetes, and amounts of hemorrhage. The correlation between FA ratio and improvement of motor function was analyzed by Pearson’s correlation analysis.
Results
Motor function improvement was significantly correlated with FA ratio. Volume of hemorrhage related with motor function at admission, but it is useless for estimating prognosis. Hypertension and diabetes are not correlated with motor function improvement in this study.
Conclusion
In patients with hypertensive ICH, FA ratio that is calculated from FA values of MR DTI could be a prognostic factor of motor function improvement.
Key Words: Intracranial Hemorrhage, HypertensiveㆍDiffusion MRIㆍCorticospinal TractㆍFunction Recovery


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