| Gamma Knife Surgery for Pituitary Tumors in Geriatric Patients |
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Dong Hyun Chun , Moo Seong Kim , Jae Won Jeong , Seong Tae Kim , Gun Soo Lee , Won Hee Lee |
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Department of Neurosurgery, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea |
| 고령의 뇌하수체종양 환자의 감마나이프 수술 |
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천동현·김무성·정재원·김성태·이근수·이원희 |
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인제대학교 의과대학 부산백병원 신경외과학교실 |
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| Abstract |
Objective
Pituitary adenomas represent approximately 15% of all intracranial tumors and there is continuing controversy over the ideal method of therapy for pituitary adenoma. We present our results that managed over 70 years old patients with pituitary tumor using Gamma knife surgery.
Methods
Eighteen cases of pituitary adenomas were treated with Gamma knife from November 1994 to December 2014 in our institute. There were 2 cases of prolactinoma, 16 cases of non-functioning adenoma. The mean tumor volume was 5.9 cc (0.86-15.1 cc) and the mean marginal dose was 15.4 Gy (range 11-25 Gy) and the mean maximal dose was 28.7 Gy (range 22-50 Gy). The mean follow-up period was 26.5 months (range 6-50 months).
Results
On follow-up radiologic study after Gamma knife surgery, 8 cases showed reduction in size, 9 cases showed no change and 1 cases showed increase in size. In prolactinomas, 1 case reduced tumor size and 1 case showed no change of tumor size. Seven cases out of 16 non-fuctioning adenomas showed size reduction and remain 8 cases unchanged its size. In the hormonal result, 1 out of 2 prolactinoma patients had decreased prolactin secretion and 1 case showed clinical cure.
Conclusion
Non-functioning adenomas, prolactinoma showed high control rates even with lower dose treatment. Gamma knife radiosurgery is very effective treatment for geriatric pituitary tumors with minimal side effects. |
| Key Words:
Pituitary adenomasㆍNon functioning adenomas |
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